![]() ![]() The reason that TFOS sponsored and organized this initiative is because TFOS is a non-profit organization with a mission to advance eye and tear film research, knowledge and education. To increase our understanding of dry eye disease, the Tear Film & Ocular Surface Society (TFOS) launched the Dry Eye Workshop II (TFOS DEWS II) in March 2015, which lasted for more than two years, and involved the efforts of over 150 eye doctors and researchers around the world. Global Effort To Increase Understanding Of Dry Eye Disease 1 Design of clinical trials for dry eye disease treatment Management and therapy of dry eye diseaseġ1. Role of sex, gender, and hormones in dry eye diseaseġ0. ![]() Classification and definition of dry eye diseaseĤ. Global effort to increase understanding of dry eye diseaseĢ. There is no single approach to dry eye management that will suit all patients.ġ. ![]() The treatment of dry eye remains something of an art, requiring an individualized approach for affected patients. While certain treatments may be specifically indicated for one aspect of a patient’s condition, a number of therapies may be appropriate to manage a patient presenting with dry eye. The ultimate goal of dry eye management is to restore the homeostasis of the surface of the eye and tear film. ![]() Determining the major causative factors behind the dry eye is critical to selecting the appropriate management. The management of dry eye disease can be challenging due to its multifactorial etiology. A dry eye diagnosis then requires a positive score on one of two specific symptom questionnaires, followed by at least one positive clinical sign indicating a reduced non-invasive tear break-up time (a measure of tear film stability), an elevated or a large inter-eye disparity in osmolarity (tear saltiness), or ocular surface damage indicated by dye staining. The most common cause of evaporative dry eye is meibomian gland dysfunction.Ī recommended sequence of tests for the diagnosis of dry eye disease first utilizes questions to exclude conditions that mimic dry eye. The core mechanism of dry eye disease is evaporation-induced tear hyperosmolarity (higher salt concentration than normal), which is the trigger for a cascade of events leading to eye surface damage and inflammation. Two forms of dry eye are recognized, aqueous deficient resulting from reduced tear secretion, and evaporative resulting from excessive tear evaporation. reading, driving, use of digital devices), sleep deprivation, reduced energy, poor general health, and often depression. Moderate to severe dry eye can be life-altering and may be associated with eye pain, limitations in performing daily activities (e.g. This symptomatic disease is characterized by an unstable and a more concentrated (termed hyperosmolar) tear film, which leads to increased inflammation and damage to eye structures and nerves.
0 Comments
Leave a Reply. |